MECP2 (81-170) Mouse Monoclonal Antibody [Clone ID: 4B6]

CAT#: AM31107PU-N

MECP2 (81-170) mouse monoclonal antibody, clone 4B6, Purified

Product Images

MECP2 monoclonal antibody clone 4B6. Western Blot analysis of MECP2 expression in rat muscle.

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  MECP2 monoclonal antibody clone 4B6 Western Blot analysis of MECP2 expression in MCF-7.

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  MECP2 monoclonal antibody clone 4B6. Western Blot analysis of MECP2 expression in NIH/3T3.

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  Detection limit for recombinant GST tagged MECP2 is approximately 1ng/ml as a capture antibody.

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  Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)

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Specifications

Product Data

• Clone Name: 4B6
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot: 1/500 - 1/1000.
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: MECP2 antibody was raised against MECP2 (81 a.a. ~ 170 a.a) partial recombinant protein with GST tag.
• Specificity: This antibody reacts to MECP2 at aa 81-170.
• Formulation: PBS, pH 7.4
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens methyl-CpG binding protein 2 (MECP2), transcript variant 2
• Database Link:
  Entrez Gene 17257 MouseEntrez Gene 29386 RatEntrez Gene 4204 Human
• Background: DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters.
• Synonyms: MeCP-2 protein

Reference Data

• Protein Families: Druggable Genome