FBXO11 Mouse Monoclonal Antibody [Clone ID: 4C12]

CAT#: AM31114PU-N

FBXO11 mouse monoclonal antibody, clone 4C12, Purified

Product Images

Detection limit for recombinant GST tagged FBXO11 is approximately 0.1ng/ml as a capture antibody.

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  Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Immunofluorescence of monoclonal antibody to FBXO11 on HeLa cell. [antibody concentration 10 ug/ml]

Specifications

Product Data

• Clone Name: 4C12
• Applications: ELISA, IF, IHC, WB
• Recommended Dilution: ELISA.
  Immunofluorescence: 10 µg/ml.
  Immunohistochemistry on Paraffin Sections: 2.5 µg/ml.
  Western Blot.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: FBXO11 antibody was raised against recombinant protein
• Specificity: This antibody reacts to FBXO11.
• Formulation: PBS, pH 7.2
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: 0.49 mg/ml
• Purification: Affinity chromatography on Protein A
• Gene Name: Homo sapiens F-box protein 11 (FBXO11), transcript variant 4
• Database Link:
  Entrez Gene 80204 Human
• Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
• Synonyms: F-box only protein 11, FBX11, VIT1, UG063H01, Vitiligo-associated protein 1

Reference Data

• Protein Families: Druggable Genome