PAX5 Mouse Monoclonal Antibody [Clone ID: 8F9]

CAT#: AM31120PU-N

PAX5 mouse monoclonal antibody, clone 8F9, Purified


USD 480.00

2 Weeks*

Size
    • 50 ug

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Specifications

Product Data
Clone Name 8F9
Applications ELISA, IHC, WB
Recommended Dilution ELISA.
Immunohistochemistry on Paraffin Sections: 5 µg/ml.
Western Blot: 1/500 - 1/1000.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen PAX5 (NP_057953, 192 a.a. ~ 302 a.a) partial recombinant protein with GST tag.
Specificity This antibody recognizes PAX5
Formulation PBS, pH 7.2
State: Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Protein A Chromatography
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens paired box 5 (PAX5), transcript variant 1
Background Pax-5 is a B cell specificactivator protein (BSAP). In the early stages of B cell developmemt, Pax-5 influences the expression of several B-cell-specific genes, such as CD19 and CD20. Pax-5 is expressed primarily inpro-, pre-, and mature B cells, but not inplasma cells. Interestingly, Pax-5 mRNA is transiently detected in the mesencephalon and spinal cord during embryogenesis. Expression then shifts to the fetal liver and correlates with the onset of B lymphopoiesis. This indicates that Pax-5 is important in B cell development, but may also have a role in proper neuronal development.
Synonyms Pax-5, BSAP
Reference Data
Protein Families Transcription Factors

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.