MEOX 2 (MEOX2) (1-304) Mouse Monoclonal Antibody [Clone ID: 6A5]

CAT#: AM31128PU-N

MEOX 2 (MEOX2) (1-304) mouse monoclonal antibody, clone 6A5, Purified

Product Images

MEOX2 monoclonal antibody clone 6A5 Western Blot analysis of MEOX2 expression in HeLa.

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  MEOX2 monoclonal antibody clone 6A5. Western Blot analysis of MEOX2 expression in PC-12.

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  MEOX2 monoclonal antibody clone 6A5. Western Blot analysis of MEOX2 expression in NIH/3T3.

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  Detection limit for recombinant GST tagged MEOX2 is approximately 0.3ng/ml as a capture antibody.

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  Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Immunofluorescence of monoclonal antibody to MEOX2 on HeLa cell. [antibody concentration 10 ug/ml]

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Specifications

Product Data

• Clone Name: 6A5
• Applications: ELISA, IF, IHC, WB
• Recommended Dilution: ELISA.
  Immunofluorescence: 10 µg/ml.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot: 1/500 - 1/1000.
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: MEOX2 (AAH17021, 1 a.a. ~ 304 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Specificity: This antibody reacts to MEOX2 at aa 1-304.
• Formulation: PBS, pH 7.4
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens mesenchyme homeobox 2 (MEOX2)
• Database Link:
  Entrez Gene 17286 MouseEntrez Gene 29279 RatEntrez Gene 4223 Human
• Background: Mesodermal transcription factor that plays a key role in somitogenesis and is required for sclerotome development (By similarity). Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner (PubMed:22206000). May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.
• Synonyms: GAX, MOX2, Growth arrest-specific homeobox, Mesenchyme homeobox 2, Homeobox protein MOX-2

Reference Data

• Protein Families: Transcription Factors