IL13 receptor alpha 2 (IL13RA2) Mouse Monoclonal Antibody [Clone ID: B-D13]

CAT#: AM31179RP-N

IL13 receptor alpha 2 (IL13RA2) mouse monoclonal antibody, clone B-D13, PE

Specifications

Product Data

• Clone Name: B-D13
• Applications: FC
• Recommended Dilution: Flow Cytometry: Use 10 µl to label 10⁶ cells or 100 µl of whole blood.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: IL-13Ra2 transfected CHO cell line.
  Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells.
• Specificity: Recognizes the soluble antigen.
  Recognizes the IL-13 receptor a2 (IL-13 Ra2), a 74 kDa protein.
  Tested on monocyte activation (Secretion IL-6).
• Formulation: PBS
  Label: PE
  State: Lyophilized purified IgG fraction
  Stabilizer: 5% BSA
  Preservative: 0.09% Sodium Azide
• Reconstitution Method: Restore with 1 ml deionised water.
• Purification: Ion Exchange Chromatography
• Conjugation: PE
• Storage: Store the antibody after reconstitution at 2-8°C.
  DO NOT FREEZE!
• Stability: Shelf life: Six months from despatch.
• Gene Name: Homo sapiens interleukin 13 receptor subunit alpha 2 (IL13RA2)
• Database Link:
  Entrez Gene 3598 Human
• Background: IL13 receptor alpha 2 belongs to the type I cytokine receptor family.
  Contains 1 fibronectin type-III domain.
  Binds as a monomer with high affinity to interleukin-13 (IL13), but not to interleukin-4 (IL4).
  The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
  The box 1 motif is required for JAK interaction and/or activation.
• Synonyms: Interleukin-13 receptor alpha-2 chain, IL13RA2, IL-13RA-2, IL13R, IL13 receptor alpha-2, IL-13R-alpha-2

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Jak-STAT signaling pathway