CD2 Mouse Monoclonal Antibody [Clone ID: B-E2]

CAT#: AM31181BT-N

CD2 mouse monoclonal antibody, clone B-E2, Biotin


USD 280.00

2 Weeks*

Size
    • 1 ml (100 Tests)

Product Images

Specifications

Product Data
Clone Name B-E2
Applications FC, IHC
Recommended Dilution Flow Cytometry: Use 10 µl to label 106 cells or 100 µl of whole blood.
Immunohistochemistry.
Reactivities Human
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Human thymocytes.
Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells
Specificity Recognizes the Lymphocyte Function associated Antigen-2 (LFA-2), a 50 kDa protein.
Formulation PBS containing 5% BSA as stabilizer and 0.09% Sodium Azide as preservative
Label: Biotin
State: Lyophilized purified IgG fracgtion.
Reconstitution Method Restore with 1.0 ml deionised water.
Purification Ion Exchange Chromatography.
Conjugation Biotin
Storage Prior to reconstitution store at 2-8°C.
Following reconstitution store undiluted at 2-8°C for one month
or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens CD2 molecule (CD2), transcript variant 2
Background CD2 which is also known as E-rosette receptor, T11 and lymphocyte-function antigen-2 (LFA-2) is expressed on T cells, thymocytes, and subset of natural killer cells. Human CD2 functions as the receptor for sheep erythrocytes, human CD58 (LFA-3), and CD15s (Sialyl Lewis X). p56lck, p59fyn, CD3eta and CD3epsilon are tyrosine-phosphorylated after CD2 stimulation. CD2 play a role in T cell activation, T- or NK-cell-mediated cytolysis, apoptosis in activated peripheral T cells, and regulation of T cell anergy.
Synonyms SRBC, Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs), Hematopoietic cell lineage

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.