CD2 Mouse Monoclonal Antibody [Clone ID: B-E2]

CAT#: AM31181PU-N

CD2 mouse monoclonal antibody, clone B-E2, Purified

Product Images

A typical staining pattern with the B-E2 monoclonal antibody of lymphocytes.

Specifications

Product Data

• Clone Name: B-E2
• Applications: FC, IHC
• Recommended Dilution: Flow Cytometry: Use 10 µl to label 106 cells or 100 µl of whole blood.
  Immunohistochemistry.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Human thymocytes.
  Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells
• Specificity: Recognizes the Lymphocyte Function associated Antigen-2 (LFA-2), a 50 kDa protein.
• Formulation: PBS containing 1% BSA as stabilizer and 0.09% Sodium Azide as preservative.
  State: Purified
  State: Liquid purified IgG fraction.
• Purification: Ion Exchange Chromatography.
• Storage: Store the antibody undiluted at 2-8°C.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens CD2 molecule (CD2), transcript variant 2
• Database Link:
  Entrez Gene 914 Human
• Background: CD2 which is also known as E-rosette receptor, T11 and lymphocyte-function antigen-2 (LFA-2) is expressed on T cells, thymocytes, and subset of natural killer cells. Human CD2 functions as the receptor for sheep erythrocytes, human CD58 (LFA-3), and CD15s (Sialyl Lewis X). p56lck, p59fyn, CD3eta and CD3epsilon are tyrosine-phosphorylated after CD2 stimulation. CD2 play a role in T cell activation, T- or NK-cell-mediated cytolysis, apoptosis in activated peripheral T cells, and regulation of T cell anergy.
• Synonyms: SRBC, Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Hematopoietic cell lineage