CD44 Mouse Monoclonal Antibody [Clone ID: B-F24]

CAT#: AM31185AF-N

CD44 mouse monoclonal antibody, clone B-F24, Azide Free

Product Images

A typical staining pattern with the B-F24 monoclonal antibody of lymphocytes

Specifications

Product Data

• Clone Name: B-F24
• Applications: ELISA, FC, FN, IP
• Recommended Dilution: Immunoprecipitation.
  Flow Cytometry.
  Functional Assay: Triggers T Lymphocyte Aggregation. Enhances hyaluronan binding to CD44.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: U937 cell line
• Specificity: Recognises the soluble Hyaluronate Cell Adhesion Molecule (H-CAM), a 85-250 kDa protein.
• Formulation: Phosphate-buffered saline.
  Sterile-filtered through 0.22 µm.
  Carrier and preservative free.
  State: Azide Free
  State: Liquid purfied Ig fraction.
• Concentration: lot specific
• Purification: Ion Exchange Chromatography.
• Storage: Store the antibody undiluted at 2-8°C.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens CD44 molecule (Indian blood group) (CD44), transcript variant 1
• Database Link:
  Entrez Gene 960 Human
• Background: CD44 is a type 1 transmembrane glycoprotein also known as Phagocytic Glycoprotein 1 (pgp 1) and HCAM. CD44 is the receptor for hyaluronate and exists as a large number of different isoforms due to alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type 1 transmembrane protein. Other isoforms contain glycosaminoglycans and are expressed on hematopoietic and non hematopoietic cells. CD44 is involved in adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix.
• Synonyms: LHR, MDU2, MDU3, MIC4, CDw44, Epican, ECMR-III, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, PGP-1

Reference Data

• Protein Families: Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway, Transmembrane
• Protein Pathways: ECM-receptor interaction, Hematopoietic cell lineage