VCAM1 Mouse Monoclonal Antibody [Clone ID: B-K9]

CAT#: AM31190AF-N

VCAM1 mouse monoclonal antibody, clone B-K9, Azide Free


USD 270.00

2 Weeks*

Size
    • 200 ug

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Specifications

Product Data
Clone Name B-K9
Applications ELISA, FC, FN
Recommended Dilution ELISA.
Flow Cytometry.
Functional Assay: Blocks the cell attachment to VCAM-1.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Activated Human umbilical vein endothelial.
cells.
Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells.
Specificity Recognizes the Vascular Cellular Adhesion Molecule-1 (VCAM-1), a 110 kDa protein.
Recognizes the soluble antigen.
Formulation Phosphate-buffered saline without Carrier and preservatives.
This prodcut is sterile-filtered through 0.22 µm and treated to remove Endotoxins.
State: Azide Free
State: Liquid purified IgG fraction.
Concentration lot specific
Purification Ion Exchange Chromatography.
Storage Store the antibody undiluted at 2-8°C.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens vascular cell adhesion molecule 1 (VCAM1), transcript variant 1
Background CD106 / VCAM-1 (vascular cell adhesion molecule-1) is an Ig-like cell surface adhesion molecule binding VLA-4 integrin. VCAM-1 is a potent T cell costimulatory molecule taking
part in their positive selection and survival, as well as in adhesion, transendothelial migration and activation of peripheral T cells. VCAM-1 is also involved in endothelial cell-cell contacts.
Whereas VCAM-1 normally mediates leukocyte extravasion to sites of tissue inflammation, tumour cells can use overexpressed VCAM-1 to escape T cell immunity. Soluble form of VCAM-1 (sVCAM-1) is an inflammatory marker and can be used also in prognosis of subsequent cariovascular events following acute coronary syndromes.
Synonyms V-CAM 1, INCAM-100, L1CAM, VCAM-1
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs), Leukocyte transendothelial migration

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.