CD4 Mouse Monoclonal Antibody [Clone ID: B-A1]

CAT#: AM31216AF-N

CD4 mouse monoclonal antibody, clone B-A1, Azide Free

Product Images

A typical staining pattern with the B-A1 monoclonal antibody of lymphocytes

Specifications

Product Data

• Clone Name: B-A1
• Applications: FC, FN, IHC
• Recommended Dilution: Flow Cytometry.
  Immunohistochemistry: 1/50.
  Functional Assay: Inhibits Mixed Lymphocyte Culture.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Human thymocytes and jurkat cell lines.
  Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells.
• Specificity: This antibody recognizes a 55 kDa protein.
• Formulation: Phosphate-buffered saline.
  Sterile-filtered through 0.22 µm and treated to remove endotoxins.
  Carrier and preservative free
  State: Azide Free
  State: Liquid purfied Ig fraction
• Concentration: 1.0 mg/ml
• Purification: Ion Exchange Chromatography
• Gene Name: Homo sapiens CD4 molecule (CD4), transcript variant 1
• Database Link:
  Entrez Gene 920 Human
• Background: CD4, a single chain transmembrane glycoprotein, is found on a T cell subset (helper/inducer) representing 45 % of peripheral blood lymphocytes. It is also present on 80 % of thymocytes and at a lower level on monocytes. It is involved in recognition of antigen presented along with MHC class II by APCs. It serves as receptor for HIV.
• Synonyms: T-cell surface antigen T4/Leu-3
• Note: Kd: 0.142 nM

Reference Data

• Protein Families: Adult stem cells, Druggable Genome, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transmembrane
• Protein Pathways: Antigen processing and presentation, Cell adhesion molecules (CAMs), Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway