IL2 Mouse Monoclonal Antibody [Clone ID: B-G5]

CAT#: AM31260FC-N

IL2 mouse monoclonal antibody, clone B-G5, FITC


USD 280.00

2 Weeks*

Size
    • 1 ml (100 Tests)

Product Images

Specifications

Product Data
Clone Name B-G5
Applications FC
Recommended Dilution Flow Cytometry (Intra-cytoplasmic).
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Natural Human IL-2
Specificity Recognizes both natural and recombinant Human Interleukin-2 (IL-2).
Formulation PBS containing 5% BSA as stabilizer and and 0.09% Sodium Azide as presrevative.
Label: FITC
State: Liquid purified IgG fraction.
Purification Ion Exchange Chromatography.
Conjugation FITC
Storage Store the antibody undiluted at 2-8°C.
DO NOT FREEZE!
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens interleukin 2 (IL2)
Background Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells.
Synonyms IL-2, TCGF
Reference Data
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Allograft rejection, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Jak-STAT signaling pathway, T cell receptor signaling pathway, Type I diabetes mellitus

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.