IL2 Mouse Monoclonal Antibody [Clone ID: B-G5]

CAT#: AM31260RP-N

IL2 mouse monoclonal antibody, clone B-G5, PE


USD 340.00

2 Weeks*

Size
    • 1 ml (100 Tests)

Product Images

Specifications

Product Data
Clone Name B-G5
Applications FC
Recommended Dilution Flow Cytometry (Intra-cytoplasmic): Use 10 µl of antibody to label 5x105 cells.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Natural Human IL2
Specificity Recognizes both natural and recombinant Human Interleukin-2 (IL-2).
Formulation PBS
Label: PE
State: Lyophilized purified IgG fraction
Stabilizer: 5% BSA
Preservative: 0.09% Sodium Azide
Reconstitution Method Restore with 1 ml deionized water.
Purification Ion Exchange Chromatography
Conjugation PE
Storage Store the antibody at 2-8°C after reconstitution. 
DO NOT FREEZE!
Stability Shelf life: six months from despatch.
Gene Name Homo sapiens interleukin 2 (IL2)
Background Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells.
Synonyms IL-2, TCGF
Reference Data
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Allograft rejection, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Jak-STAT signaling pathway, T cell receptor signaling pathway, Type I diabetes mellitus

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.