IL12A Mouse Monoclonal Antibody [Clone ID: B-T21]

CAT#: AM31263AF-N

IL12A mouse monoclonal antibody, clone B-T21, Azide Free


USD 470.00

2 Weeks*

Size
    • 500 ug

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Specifications

Product Data
Clone Name B-T21
Applications FC, FN
Recommended Dilution Flow Cytometry (Intra-cytoplasmic).
Functional Assay: Blocks IL-12 induced proliferation on PHA and IL-2 activated lymphocytes.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Recombinant Human IL-12.
Specificity This antibody recognizes both natural and recombinant Human IL-12 p35 + p70
Formulation Phosphate-buffered saline without Carrier and preservatives.
This prodcut is sterile-filtered through 0.22 µm and treated to remove Endotoxins.
State: Azide Free
State: Liquid purified IgG fraction
Concentration lot specific
Purification Ion Exchange Chromatography
Storage Store the antibody undiluted at 2-8°C.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens interleukin 12A (IL12A)
Background Interleukin 12 (IL12) is an important cytokine produced by a variety of immune effector cells that leads to a type 1 helper T cell (Th1) response. IL12 also directs T cells to the skin via induction of cutaneous lymphocyte antigen (CLA) expression. Interleukin 12 is a heterodimeric cytokine (p70), composed of two covalently linked subunits, p35 and p40 and is secreted primarily by activated B cells.
Synonyms IL-12A, IL-12 subunit p35, NKSF1, CLMF p35
Reference Data
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Allograft rejection, Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway, Type I diabetes mellitus

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.