IL6R Mouse Monoclonal Antibody [Clone ID: B-R6]

CAT#: AM31357AF-N

IL6R mouse monoclonal antibody, clone B-R6, Azide Free

Product Images

A typical staining pattern with the B-R6 monoclonal antibody of U266 cell line

Specifications

Product Data

• Clone Name: B-R6
• Applications: FC, FN, IHC, IP
• Recommended Dilution: ELISA.
  Flow Cytometry.
  Immunoprecipitation.
  Immunohistochemistry on Frozen Sections.
  Functional Assay: Blocks IL-6 induced proliferation of XG-1 cells. Inhibits IL-6 binding to its receptor.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: gp80 transfected CHO cell line
• Specificity: This antibody recognises the Interleukin-6 Ra subunit, IL-6 Ra, IL-6 R, a 80 kDa protein.
• Formulation: Phosphate-buffered saline.
  Sterile-filtered through 0.22 µm and treated to remove endotoxins.
  Carrier and preservative free
  State: Azide Free
  State: Liquid purified IgG fraction
• Concentration: lot specific
• Purification: Ion Exchange Chromatography
• Storage: Store the antibody undiluted at 2-8°C.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens interleukin 6 receptor (IL6R), transcript variant 1
• Database Link:
  Entrez Gene 3570 Human
• Synonyms: Interleukin-6 receptor subunit alpha, IL-6R-alpha, IL-6R 1, IL6 Receptor alpha

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway