Botulinum neurotoxin type A (1177-1195) Mouse Monoclonal Antibody [Clone ID: B29M]

CAT#: AM31426PU-N

Botulinum neurotoxin type A (1177-1195) mouse monoclonal antibody, clone B29M, Purified

Specifications

Product Data

• Clone Name: B29M
• Applications: ELISA, WB
• Recommended Dilution: ELISA.
  Western Blot.
• Host: Mouse
• Isotype: IgM
• Clonality: Monoclonal
• Immunogen: Synthetic peptide of C. botulinum toxin A heavy chain, a.a. 1177-1195
• Specificity: This antibody recognizes Clostridium botulinum Type A Neurotoxin Heavy Chain (amino acids 1177-1195).
  Weak cross-reactivity with Type B and Type E toxoids.
• Formulation: PBS, pH 7.4
  State: Purified
  State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE)
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Euglobulin precipitation
• Storage: Store the antibody undiluted at 2-8°C.
• Stability: Shelf life: one year from despatch.
• Background: Clostridium botulinum neurotoxins are zinc-dependent proteases that block the release of acetylcholine from peripheral cholinergic nerve endings by targeting specific membrane proteins including synaptosomal-associated proteins (SNAP), vesicle-associated membrane proteins (VAMP), and syntaxins. Neurotoxin A is characteristically associated with human botulism and known to target and hydrolyse the 197-Gln-|-Arg-198 bond of SNAP-25.
• Synonyms: BoNT/A, Clostridium botulinum Toxin A, Bontoxilysin-A, BOTOX