Lymphotactin (XCL1) (22-114) Mouse Monoclonal Antibody [Clone ID: 1E1]

CAT#: AM31697PU-N

Lymphotactin (XCL1) (22-114) mouse monoclonal antibody, clone 1E1, Purified

Product Images

Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Clone Name: 1E1
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: xCL1 (NP_002986, 22 a.a. ~ 114 a.a) partial recombinant protein with GST tag
• Specificity: Recognizes Human XCL1 / Lymphotactin.
• Formulation: PBS, pH 7.4
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A Chromatography
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens myosin, heavy chain 9, non-muscle (MYH9)
• Database Link:
  Entrez Gene 4627 HumanEntrez Gene 6375 Human
• Background: Lymphotactin, also known as XCL1, is member of gamma or C subfamily of chemokines. It is found in high levels in spleen, thymus, intestine and peripheral blood leukocytes, and at lower levels in lung, prostate gland and ovary. The expression of lymphotactin is restricted to activated T cells such as activated CD8+ T cells and other calss IMHC restricted T cells. Since lymphotactin is produced by lymphocytes and acts on lymphocytes, it is speculated that it is a messenger in T cell chemoattraction.
• Synonyms: LTN, Lymphotaxin, ATAC, SCM-1-alpha, SCYC1

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Regulation of actin cytoskeleton, Tight junction, Viral myocarditis