LI Cadherin (CDH17) Mouse Monoclonal Antibody [Clone ID: 3H2]

CAT#: AM31737PU-N

LI Cadherin (CDH17) mouse monoclonal antibody, clone 3H2, Purified

Product Images

Detection limit for recombinant GST tagged CDH17 is approximately 0.03ng/ml as a capture antibody.

• 

  Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Clone Name: 3H2
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: CDH17 antibody was raised against CDH17 (NP_004054, 24 a.a. ~ 132 a.a) partial recombinant protein with GST tag.
• Specificity: Recognizes Cadherin-17
• Formulation: PBS, pH 7.2
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A Chromatography
• Storage: Store the antibody (in aliquots) at -20°C or -80°C.
  Avoid freeze-thaw cycles.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens cadherin 17 (CDH17), transcript variant 2
• Database Link:
  Entrez Gene 1015 Human
• Background: The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including catenin beta, to regulate cadherin function. LI-cadherin (for liver-intestine-cadherin) expression is restricted to liver and intestine tissues and is specifically localized to the basolateral domain of hepatocytes and enterocytes.
• Synonyms: HPT-1, HPT1, CDH17

Reference Data

• Protein Families: Transmembrane