OLIG2 Mouse Monoclonal Antibody [Clone ID: 3C9]

CAT#: AM31746PU-N

OLIG2 mouse monoclonal antibody, clone 3C9, Purified

Product Images

Human Brain, Oligodendroglia: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Clone Name: 3C9
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot: 1/500 - 1/1000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: OLIG2 antibody was raised against OLIG2 (NP_005797, 2 a.a. ~ 78 a.a) full length recombinant protein with GST tag.
• Specificity: Recognizes Human OLIG2
• Formulation: PBS, pH 7.2
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: 0.49 mg/ml
• Purification: Protein A Chromatography
• Gene Name: Homo sapiens oligodendrocyte lineage transcription factor 2 (OLIG2)
• Database Link:
  Entrez Gene 10215 Human
• Background: This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome.
• Synonyms: OLIG2, BHLHB1, PRKCBP2, RACK17, Oligodendrocyte transcription factor 2, Oligo2, bHLHB1

Reference Data

• Protein Families: Druggable Genome, Transcription Factors