SP140 Mouse Monoclonal Antibody [Clone ID: 3F9]

CAT#: AM31747PU-N

SP140 mouse monoclonal antibody, clone 3F9, Purified

Product Images

Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Clone Name: 3F9
• Applications: ELISA, IHC
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: SP140 antibody was raised against SP140 (NP_009168, 504 a.a. ~ 613 a.a) partial recombinant protein with GST tag.
• Specificity: Recognizes SP140
• Formulation: PBS, pH 7.2
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: 0.5 mg/ml
• Purification: Protein A Chromatography
• Gene Name: Homo sapiens SP140 nuclear body protein (SP140), transcript variant 1
• Database Link:
  Entrez Gene 11262 Human
• Background: SP140 is the nuclear body protein found specifically in all NP cells. HIV 1 infection induced its partial dispersal from nuclear bodies into cytosolic colocalization with viral infection. It is also known as nuclear domain 10, PML oncogenic domain, and KR body. SP140 be involved in the pathogenesis of acute promyelocytic leukemia and viral infection.
• Synonyms: Nuclear antigen Sp-140, Speckled 140 kDa, LYSP100

Reference Data

• Protein Families: Druggable Genome, Transcription Factors