PIM1 Mouse Monoclonal Antibody [Clone ID: X1]

CAT#: AM31764PU-N

PIM1 mouse monoclonal antibody, clone X1, Purified

Product Images

Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)

• 

  Immunofluorescence of monoclonal antibody to PIM1 on HeLa cell. [antibody concentration 10 ug/ml]

Specifications

Product Data

• Clone Name: X1
• Applications: ELISA, IF, IHC
• Recommended Dilution: ELISA.
  Immunofluorescence: 10 µg/ml.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: PIM1 antibody was raised against pIM1 (AAH20224, 1 a.a. ~ 314 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Specificity: This antibody reacts to PIM1.
• Formulation: PBS, pH 7.2
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens Pim-1 proto-oncogene, serine/threonine kinase (PIM1), transcript variant 1
• Database Link:
  Entrez Gene 5292 Human
• Background: PIM-1, an immediate early gene in the PIM subfamily of kinases, has been implicated in the regulation of proliferation, differentiation and cell survival of lymphoid and myeloid cells. PIM-1 is a cytoplasmic modulator of the interleukin-3 signal transduction pathway. Two isoforms of PIM-1 exist: the larger protein is an amino-terminal extension of the smaller protein and is synthesized by alternative translation initiation at an upstream CUG codon.
• Synonyms: Pim-1

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase
• Protein Pathways: Acute myeloid leukemia, Jak-STAT signaling pathway