FOXO3 (361-460) Mouse Monoclonal Antibody [Clone ID: 4E8]

CAT#: AM31786PU-N

FOXO3 (361-460) mouse monoclonal antibody, clone 4E8, Purified


USD 480.00

2 Weeks*

Size
    • 50 ug

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Specifications

Product Data
Clone Name 4E8
Applications ELISA, IHC, WB
Recommended Dilution ELISA.
Immunohistochemistry on Paraffin Sections: 5 µg/ml.
Western Blot: 1/500 - 1/1000.
Reactivities Human
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen FOXO3 antibody was raised against fOXO3A (AAH21224, 361 a.a. ~ 460 a.a) partial recombinant protein with GST tag.
Specificity This antibody reacts to FOXO3 / FOXO3A at aa 361-460.
Formulation PBS, pH 7.4
State: Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Affinity chromatography on Protein A
Storage Store the antibody at -20°C to -80°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens forkhead box O3 (FOXO3), transcript variant 1
Background Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
Synonyms FOXO3A, AF6q21 protein
Reference Data
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Chemokine signaling pathway, Endometrial cancer, Neurotrophin signaling pathway, Non-small cell lung cancer

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.