INPP5F (OCRL) Mouse Monoclonal Antibody [Clone ID: 4A6]

CAT#: AM31806PU-N

INPP5F (OCRL) mouse monoclonal antibody, clone 4A6, Purified

Product Images

OCRL monoclonal antibody LS-B6106, Western Blot analysis of OCRL expression in Hela NE.

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  Western Blot analysis of OCRL expression in transfected 293T cell line by OCRL monoclonal antibody.

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  Detection limit for recombinant GST tagged OCRL is approximately 0.1ng/ml as a capture antibody.

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  Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Clone Name: 4A6
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot: 1/500 - 1/1000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: OCRL antibody was raised against oCRL (NP_000267, 146 a.a. ~ 240 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Specificity: This antibody reacts to OCRL.
• Formulation: PBS, pH 7.2
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage: Store the antibody at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens OCRL, inositol polyphosphate-5-phosphatase (OCRL), transcript variant a
• Database Link:
  Entrez Gene 4952 Human
• Background: RelevanceConverts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate. Also converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate. May function in lysosomal membrane trafficking by regulating the specific pool of phosphatidylinositol 4,5-bisphosphate that is associated with lysosomes.
• Synonyms: INPP5F, OCRL1, OCRL-1

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system