MAG Mouse Monoclonal Antibody [Clone ID: 3C7]

CAT#: AM31812PU-N

MAG mouse monoclonal antibody, clone 3C7, Purified

Product Images

Western Blot analysis of MAG expression in Jurkat cell lysate.

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  Detection limit for recombinant GST tagged MAG is 0.1 ng/ml as a capture antibody.

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  Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Clone Name: 3C7
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 2.5 µg/ml.
  Western Blot: 1/500 - 1/1000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: MAG antibody was raised against MAG (NP_002352, 119 a.a. ~ 209 a.a) partial recombinant protein with GST tag.
  MW of the GST tag alone is 26 KDa.
• Specificity: This antibody recognizes Human MAG.
  Other species not tested.
• Formulation: PBS, pH 7.4
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Storage: Upon receipt, store undiluted (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens myelin associated glycoprotein (MAG), transcript variant 1
• Database Link:
  Entrez Gene 4099 Human
• Background: Myelin-associated glycoprotein (MAG), a member of the immunoglobulin superfamily, is a membrane glycoprotein of 100 kDa, and is thought to be involved in the process of myelination. Axonal regeneration in the adult central nervous system (CNS) is limited by two proteins in myelin, Nogo and MAG. MAG has been implicated in the inhibition of nerve regeneration in the CNS.
• Synonyms: MAG, GMA, Siglec-4a

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs)