Factor VII (F7) (+VIIa) Mouse Monoclonal Antibody [Clone ID: AD-1]

CAT#: AM31848BT-N

Factor VII (F7) (+VIIa) mouse monoclonal antibody, clone AD-1, Biotin

Specifications

Product Data

• Clone Name: AD-1
• Applications: ELISA, WB
• Recommended Dilution: ELISA.
  Western Blot.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human Factor VII (AD-1) purified from plasma.
• Specificity: This antibody is specific for factor VII/VIIa (AD-1).
• Formulation: PBS containing 0.02% Sodium Azide as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml
  Label: Biotin
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Conjugation: Biotin
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens coagulation factor VII (F7), transcript variant 1
• Database Link:
  Entrez Gene 2155 Human
• Background: Human blood coagulation factor VII is a 50 kD, vitamin K dependent, plasma glycoprotein synthesized in the liver and secreted into the blood as a single chain zymogen of serine protease factor VIIa. Factor VII participates in a cascade of reactions leading to the coagulation of blood and contains two Epidermal Growth Factor (EGF) domains. This antibody recognizes an epitope in the factor VIIa heavy chain.
  Factor VII participates in the extrinsic pathway of blood coagulation in an Activated form called factor VIIa. Factor VII can be converted to VIIa by Factor IXa or thrombin.
• Synonyms: Proconvertin, SPCA

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Complement and coagulation cascades