SERPINB8 Mouse Monoclonal Antibody [Clone ID: anti-PI8K]
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Specifications
Product Data | |
Clone Name | anti-PI8K |
Applications | ELISA, WB |
Recommended Dilution | ELISA: 7.8 ng/ml Western Blot. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Human Proteinase Inhibitor 8 (PI8) purified from the supernatant of thrombin activated platelets. |
Specificity | This antibody is specific for Human Proteinase Inhibitor 8 (PI8). |
Formulation | PBS containing 0.02% sodium azide (NaN3) as preservative State: Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Affinity chromatography on Protein G |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens serpin peptidase inhibitor, clade B (ovalbumin), member 8 (SERPINB8), transcript variant 1 |
Database Link | |
Background | Serpins are a group of proteins with similar structures that have been shown to inhibit proteases. Many serpins, like PI8 inhibit chymotrypsin – like serine proteases (serine protease inhibitors). Human proteinase inhibitor 8 (PI8) is a widely expressed 45-kDa ovalbumin type serpin. PI8 forms a complex with Furin, a ubiquitous mammalian endoproteinase in order to inhibit it. PI8 is also a potent inhibitor of bacillus subtilis, a Gram and catalase positive bacteria commonly found in soil. |
Synonyms | Serpin B8, CAP2, CAP-2, PI8, PI-8 |
Reference Data | |
Protein Families | Druggable Genome |
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