BCL3 Hamster Monoclonal Antibody [Clone ID: Ham150-3.5]

CAT#: AM31856BT-L

BCL3 hamster monoclonal antibody, clone Ham150-3.5, Biotin


USD 515.00

2 Weeks*

Size
    • 300 ug

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Specifications

Product Data
Clone Name Ham150-3.5
Applications ELISA
Recommended Dilution This Clone has been described to work in ELISA, Western Blot and Flow Cytometry.
Reactivities Human, Mouse
Host Hamster
Isotype IgG1
Clonality Monoclonal
Immunogen Recombinant Bcl-3-6-histidine tag from Armenian Hamster.
Fusion Partner: SP2/0 myeloma.
Specificity Recognizes B-cell Leukemia/lymphoma 3
Formulation PBS containing 0.02% Sodium Azide as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml.
Label: Biotin
State: Liquid purified IgG fraction.
Concentration 0.1 mg/ml
Purification Protein G Affinity Chromatography.
Conjugation Biotin
Gene Name Homo sapiens B-cell CLL/lymphoma 3 (BCL3)
Background B cell Lymphoma 3 is a member of the IkB subfamily of inhibitors. This subfamily is part of the NF-kB transcription factor protein family and it is suggested that a balance in the concentration of various NF-kB family members regulates apoptosis and survival of activated T cells.
Bcl-3 has been shown to have versatile functions such as cytoplasmic activation of p50 homodimers, translocation to the nucleus, and modulation of the transcriptional machinery in the nucleus. Bcl-3 activity often relies on several nuclear interacting proteins such as Tip60, Jab1, Bard1, and Pirin. The Mouse Bcl-3 coding region exhibits 80% homology with Human Bcl-3 which is associated with human B-cell chronic lymphocytic leukemias (CLLs).
Bcl-3 is detected in various tissues such as spleen and other lymphoid organs.
Synonyms BCL3, BCL4, D19S37
Reference Data
Protein Families Druggable Genome, Transcription Factors

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.