BCL3 Hamster Monoclonal Antibody [Clone ID: Ham150-3.5]

CAT#: AM31856PU-N

BCL3 hamster monoclonal antibody, clone Ham150-3.5, Purified


USD 375.00

2 Weeks*

Size
    • 250 ug

Product Images

Other products for "BCL3"

Specifications

Product Data
Clone Name Ham150-3.5
Applications ELISA, FC, WB
Recommended Dilution This Clone has been described to work in ELISA, Western Blot and Flow Cytometry.
Reactivities Human, Mouse
Host Hamster
Isotype IgG1
Clonality Monoclonal
Immunogen Recombinant Bcl-3-6-histidine tag from Armenian Hamster.
Fusion Partner: SP2/0 myeloma.
Specificity Recognizes B-cell Leukemia/lymphoma 3 (Bcl-3).
Formulation PBS containing 0.02% Sodium Azide as preservative
State: Purified
State: Liquid purified IgG fraction
Concentration 1.0 mg/ml
Purification Protein G Affinity Chromatography
Gene Name Homo sapiens B-cell CLL/lymphoma 3 (BCL3)
Background B cell Lymphoma 3 is a member of the IkB subfamily of inhibitors. This subfamily is part of the NF-kB transcription factor protein family and it is suggested that a balance in the concentration of various NF-kB family members regulates apoptosis and survival of activated T cells.
Bcl-3 has been shown to have versatile functions such as cytoplasmic activation of p50 homodimers, translocation to the nucleus, and modulation of the transcriptional machinery in the nucleus. Bcl-3 activity often relies on several nuclear interacting proteins such as Tip60, Jab1, Bard1, and Pirin. The Mouse Bcl-3 coding region exhibits 80% homology with Human Bcl-3 which is associated with human B-cell chronic lymphocytic leukemias (CLLs).
Bcl-3 is detected in various tissues such as spleen and other lymphoid organs.
Synonyms BCL3, BCL4, D19S37
Reference Data
Protein Families Druggable Genome, Transcription Factors

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.