Cd27 Hamster Monoclonal Antibody [Clone ID: LG.3A10]

CAT#: AM31861AF-N

Cd27 hamster monoclonal antibody, clone LG.3A10, Azide Free


USD 735.00

2 Weeks*

Size
    • 1 mg

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Specifications

Product Data
Clone Name LG.3A10
Applications FC, FN, IHC
Recommended Dilution Flow Cytometry:
Functional Studies (stimulating).
Immunohistochemistry on Frozen Sections. 
Immunohistochemistry on Paraffin Sections:
 This clone (LG.3A10) has been reported to work on Paraffin tissue sections.
Reactivities Mouse
Host Hamster
Isotype IgG1
Clonality Monoclonal
Immunogen MCD27 tag expressing clones AR0524 and AR0530 from Armenian Hamster spleen.
Specificity Recognizes Mouse CD27 receptor.
Formulation PBS
State: Azide Free
State: Liquid purified (0.2 µm sterile filtered) IgG fraction
Preservative: None
Concentration 1.0 mg/ml
Purification Protein G Chromatography
Gene Name Mus musculus CD27 antigen (Cd27), transcript variant 1
Background CD27 is part of the Tumor Necrosis Factor (TNF) family of receptors and is lymphocyte specific. Murine CD27 is expressed on the great majority of both αβ and γδ T lymphocytes, on a small population of peripheral B cells and on a very small subset of B220+ cells in the bone marrow. Murine CD27 is found on all thymocytes except a subset of CD4-CD8- precursors.
There are two known basic functions of CD27 signaling. First, the binding of CD27 to CD70, a protein which is also expressed in T and B cells, provides costimulatory signals in lymphocyte proliferation and immunoglobulin production. Second, the association of CD27 with intracellular Siva, a proapoptotic protein, results in the induction of apoptotic events.
Synonyms TNFRSF7, CD27L receptor, T14
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.