C5R1 (C5AR1) Rat Monoclonal Antibody [Clone ID: 8D6]

CAT#: AM31865FC-N

C5R1 (C5AR1) rat monoclonal antibody, clone 8D6, FITC


USD 300.00

2 Weeks*

Size
    • 100 ug

Product Images

Other products for "C5AR1"

Specifications

Product Data
Clone Name 8D6
Applications FC
Recommended Dilution Flow Cytometry.
Immunohistochemistry on frozen sections.
Rezeptor blockage assays (unpublished results).

Tissue Distribution by Flow Cytometry Analysis:
Cell Source: Human PBL
Cell Concentration: 1x10e6 cells per test
Antibody Concentration Used: 1.0 μg/10e6 cells
Secondary Antibody: Streptavidin FITC 1/500 dilution
Reactivities Human
Host Rat
Isotype IgG2a
Clonality Monoclonal
Immunogen RBL-2H3 (rat basophilic leukemia) transfected cells expressing human C5aR on the cell surface
Donor: Lou/c rat spleen cells
Specificity This monoclonal antibody detects an epitope on the N terminus (aa 1-15) of the human C5a receptor (also known as CD88) found on human myeloid cells including granulocytes and monocytes/macrophages. It does not bind to tubular epithelial cells in situ under normal or inflammatory conditions. C5aR binds to C5a, a 74 aa peptide cleaved from complement protein C5. C5a receptor has seven transmembrane segments and is a member of the rhodopsin subfamily of G protein coupled receptors.
Formulation PBS containing 0.02% sodium azide (NaN3) as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml.
Label: FITC
State: Liquid purified Ig fraction
Label: Fluorescein isothiocyanate isomer 1
Concentration lot specific
Purification Affinity chromatography on Protein G
Conjugation FITC
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens complement C5a receptor 1 (C5AR1)
Synonyms C5a-R, C5aR, C5AR1, Complement Component 5a Receptor 1
Reference Data
Protein Families Druggable Genome, GPCR, Transmembrane
Protein Pathways Complement and coagulation cascades, Neuroactive ligand-receptor interaction

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.