Factor IX (F9) Mouse Monoclonal Antibody [Clone ID: 13F42-F6]

CAT#: AM31870PU-N

Factor IX (F9) mouse monoclonal antibody, clone 13F42-F6, Purified

Product Images

Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Clone Name: 13F42-F6
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 10 µg/ml.
  Western Blot.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length native protein (purified) (Human).
• Specificity: Recognises Factor IX
• Formulation: 0.05M Sodium Phosphate, 0.1M NaCl, 1mM EDTA, pH 6.6
  State: Purified
  State: Liquid purified IgG fraction
• Concentration: lot specific
• Purification: Protein G Chromatography
• Storage: Store at -70°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens coagulation factor IX (F9), transcript variant 1
• Database Link:
  Entrez Gene 2158 Human
• Background: Coagulation Factor IX (F9) circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease.
• Synonyms: Christmas factor, PTC
• Note: Target Molecular Weight: 56,000

Reference Data

• Protein Families: Druggable Genome, Protease, Secreted Protein
• Protein Pathways: Complement and coagulation cascades