Bst1 Rat Monoclonal Antibody [Clone ID: KT157]

CAT#: AM31882PU-N

Bst1 rat monoclonal antibody, clone KT157, Purified

Specifications

Product Data

• Clone Name: KT157
• Applications: FC
• Recommended Dilution: Flow Cytometry.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2c
• Clonality: Monoclonal
• Immunogen: T cell hybridoma J774.
  Donor: Balb/c mouse spleen cells.
  Fusion Partner: NSO Mouse Myelom a Partner.
• Specificity: This Monoclonal Antibody reacts with Mouse CD157 receptor. Other species not tested.
• Formulation: PBS containing 0.02% Sodium Azide as preservative
  State: Purified
  State: Liquid purified IgG fraction
• Concentration: 1.0 mg/ml
• Purification: Protein G Chromatography
• Gene Name: Mus musculus bone marrow stromal cell antigen 1 (Bst1)
• Database Link:
  Entrez Gene 12182 Mouse
• Background: CD157 also known as BP-3 Alloantigen or Bone marrow Stromal cell antigen-1 (BST-1), is a 38-48 KDa differentially glycosylated glycosylphosphatidylinositol (GPI) anchored cell surface glycoprotein. CD157, like CD38 belongs to a family of genetically related pleiotropic ectoenzymes. The CD157 antigen is expressed on thymocytes, bone marrow B cells, neutrophils, macrophages, stromal cells, intestinal epithelial cells, the collecting tubules of the kidney and reticular cells in lymph nodes.
  The CD157 receptor has ADP ribosyl cyclase and cyclic ADP ribose hydrolase biochemical activities. Studies show CD157 is a receptor that induces reorganization of the cytoskeleton and significant changes in cell shape. CD157 is also a mediator of neutrophil adhesion and migration. Signals mediated by CD157 act through modulation of cytosolic [Ca2+]. CD157 is also involved in cellular adhesion to the extracellular matrix.
• Synonyms: cADPr hydrolase 2, BST-1