Havcr2 Rat Monoclonal Antibody [Clone ID: 25F.1D6]

CAT#: AM31885PU-N

Havcr2 rat monoclonal antibody, clone 25F.1D6, Purified

Specifications

Product Data

• Clone Name: 25F.1D6
• Applications: FC, IHC
• Recommended Dilution: Immunohistochemistry.
  Flow Cytometry.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2a
• Clonality: Monoclonal
• Specificity: This monoclonal antibody reacts with Mouse Tim-3 type 1 transmembrane protein.
  Other species not tested.
• Formulation: PBS
  State: Purified
  State: Liquid purified IgG fraction from Ascites
  Preservative: 0.02% Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography on Protein G
• Gene Name: Mus musculus hepatitis A virus cellular receptor 2 (Havcr2)
• Database Link:
  Entrez Gene 171285 Mouse
• Background: This 281 amino acid type 1 transmembrane protein contains an immunoglobulin and mucin-like domain in its extra-cellular portion and a tyrosine phosphorylation motif in its cytoplasmic portion. Tim-3 is a member of the immunoglobulin super-family and is expressed on Th1 lymphocytes and CD11b⁺ macrophages. Tim-3 is a T helper type 1 (TH1)-specific molecule that regulates TH1 mediated auto and alloimmune responses and the induction of peripheral immunological tolerance.
• Synonyms: TIMD-3, TIM3, TIM-3, T-cell membrane protein 3, HAVCR-2