Emilin1 Rat Monoclonal Antibody [Clone ID: C11A8]
Other products for "Emilin1"
Specifications
Product Data | |
Clone Name | C11A8 |
Applications | IF, IHC, WB |
Recommended Dilution | Western Blot: 2-10 µg/ml. Immunofluorescence. Immunohistochemistry on Frozen Sections. |
Reactivities | Mouse |
Host | Rat |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Recombinant Mouse Emilin-1 |
Specificity | This antibody was selected for its ability to detect Murine Emilin-1. |
Formulation | PBS State: Purified State: Lyophilized (0.2 μm filtered) purified IgG fraction |
Reconstitution Method | Restore in sterile water to a concentration is 0.1-1.0 mg/ml. Centrifuge vial prior to opening. |
Purification | Affinity Chromatography on Protein G |
Gene Name | Mus musculus elastin microfibril interfacer 1 (Emilin1) |
Database Link | |
Background | Emilin-1 is an extracellular matrix glycoprotein localized at sites where elastin and microfibrils are in proximity. It may be responsible for anchoring smooth muscle cells to elastic fibers. It has cell adhesive capacity. Emilin-1 may have a role in the regulation of blood vessel assembly since it inhibits TGFB signaling by binding specifically to the pro-TGFB precursor and preventing its maturation by furin convertases in the extracellular space. TGFB proteins are the main regulators of blood vessel development and maintenance. |
Synonyms | EMILIN-1, EMI |
Reference Data |
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