EMILIN2 Rat Monoclonal Antibody [Clone ID: 828B3B3]

CAT#: AM31890PU-N

EMILIN2 rat monoclonal antibody, clone 828B3B3, Purified

Product Images

Western analysis using Emilin-2 antibody. 20ng of recombinant Human Emilin-2 was loaded, 5 ug/ml of anti-Human Emilin-2 was used (ECL, 45 sec expostion).

Specifications

Product Data

• Clone Name: 828B3B3
• Applications: FC, IP, WB
• Recommended Dilution: Western Blot: Use at 1-5 µg/ml.
  IF/Immunohistochemistry on Frozen Sections.
  Immunoprecipitation.
  FACS Analysis.
• Reactivities: Human
• Host: Rat
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Recombinant protein gC1q domain of EMILIN-2.
• Specificity: This antibody was selected for its ability to detect Human Emilin-2.
• Formulation: PBS
  State: Purified
  State: Lyophilized (0.2 μm filtered) purified IgG fraction
• Reconstitution Method: Centrifuge vial prior to opening.
  Restore in sterile water to the final concentration of 0.1-1.0 mg/ml.
• Purification: Affinity Chromatography on Protein G
• Gene Name: Homo sapiens elastin microfibril interfacer 2 (EMILIN2)
• Database Link:
  Entrez Gene 84034 Human
• Background: Emilins (elastin microfibril interface located proteins) are extracellular matrix glycoproteins that localize to sites with proximity to elastin and microfibrils. They consist of an N-terminal cysteine-rich EMI domain and a conserved C-terminal gC1q-like domain. Emilin-1 is abundant in elastin-rich tissues such as blood vessels, skin, heart and lung. It influences placenta formation and initial organogenesis with a later role in interstitial connective tissue. Emilin-2 is larger than Emilin-1 and contains a unique proline-rich domain. It is likely involved in the process of elastogenesis. Multimerin-2 (also known as Emilin-3 or EndoGlyx-1) is expressed during embryonic development. Multimerin-1 (also known as Emilin-4) is expressed in platelets and the endothelium of blood vessels and may act as a carrier protein for platelet factor V. Emilin-5 is encoded by the Emilin-3 gene and is sometimes referred to as Emilin-3. It contains the N-terminal cysteine-rich EMI domain but lacks the C-terminal gC1q-like domain. Emilin-5 is expressed in human mesenchymal stem cells and plays an important role in skeletal development.
• Synonyms: EMILIN-2, Protein FOAP-10