ACAT1 (N-term) Mouse Monoclonal Antibody [Clone ID: AT1.H11]

CAT#: AM31905PU-N

ACAT1 (N-term) mouse monoclonal antibody, clone AT1.H11, Aff - Purified

Product Images

Human Adrenal Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE).

Specifications

Product Data

• Clone Name: AT1.H11
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/2000.
  Immunohistochemistry on Paraffin Sections: 10 µg/ml.
  Western Blot: 1/1000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: Recombinant ACAT1 protein (N-term)
• Specificity: Recognizes specifically Human ACAT1 at N-term.
• Formulation: PBS, pH 7.4 containing 0.05% Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: 1 mg/ml
• Purification: Immunoaffinity Chromatography
• Gene Name: Homo sapiens acetyl-CoA acetyltransferase 1 (ACAT1)
• Database Link:
  Entrez Gene 38 Human
• Background: The ACAT1 mRNA encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. The ACAT gene spans approximately 27 kb and contains 12 exons interrupted by 11 introns. Defects in this gene are associated with the alpha-methylacetoaceticaciduria disorder, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone.
• Synonyms: ACAT; MAT; T2; THIL

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Butanoate metabolism, Fatty acid metabolism, Lysine degradation, Metabolic pathways, Propanoate metabolism, Pyruvate metabolism, Synthesis and degradation of ketone bodies, Terpenoid backbone biosynthesis, Tryptophan metabolism, Valine, leucine and isoleucine degradation