Aldolase (ALDOA) Mouse Monoclonal Antibody [Clone ID: 2E6]

CAT#: AM31917PU-N

Aldolase (ALDOA) mouse monoclonal antibody, clone 2E6, Purified

Product Images

Western Blot analysis of ALDOA expression in HepG2 using ALDOA Monoclonal Antibody, Clone 2E6.

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  Western Blot analysis of ALDOA expression in NIH/3T3 using ALDOA Monoclonal Antibody, Clone 2E6.

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  Formalin-Fixed, Paraffin-Embedded Human Human Kidney, Tubules stained with Aldolase A / ALDOA Antibvody (Clone 2E6) at 5 ug/ml after heat-induced antigen retrieval.

Specifications

Product Data

• Clone Name: 2E6
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot: 1/500 - 1/1000.
• Reactivities: Human, Mouse
• Host: Mouse
• Clonality: Monoclonal
• Immunogen: Recombinant protein
• Specificity: This antibody recognizes Human and Mouse ALDOA / Aldolase.
  Other species not tested.
• Formulation: PBS, pH 7.2
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A Chromatography
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens aldolase, fructose-bisphosphate A (ALDOA), transcript variant 1
• Database Link:
  Entrez Gene 11674 MouseEntrez Gene 226 Human
• Background: Fructose 1,6-bisphosphate aldolase catalyses the reversible condensation of glycerone-P and glyceraldehyde 3-phosphate into fructose 1,6-bisphosphate. Fructose 1,6-bisphosphate aldolase exists as three forms: the muscle-specific Aldolase A, the liver-specific Aldolase B, and the brain-specific Aldolase C. Aldolase A, B and C arose from a common ancestral gene from which Aldolase B first diverged. Aldolase A is one of the most highly-conserved enzymes known, with only about 2% of the residues changing per 100 million years. Aldolase B is regulated by the hormones insulin and glucagon, and has been implicated in hereditary fructose intolerance disease. Aldolase C is a polypeptide that is exclusively expressed in Purkinje cells. Aldolase C-positive Purkinje cells are organized in the cerebellum as stripes or bands that run from anterior to posterior across the cerebellum and alternate with bands of Aldolase Cnegative Purkinje cells.
• Synonyms: ALDA, NY-LU-1, Muscle-type aldolase

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Fructose and mannose metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Pentose phosphate pathway