PRUNE (PRUNE1) Mouse Monoclonal Antibody [Clone ID: 1C11]

CAT#: AM31933PU-N

PRUNE (PRUNE1) mouse monoclonal antibody, clone 1C11, Purified


USD 480.00

2 Weeks*

Size
    • 50 ug

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Specifications

Product Data
Clone Name 1C11
Applications ELISA, IHC, WB
Recommended Dilution ELISA.
Immunohistochemistry on Paraffin Sections: 5 µg/ml.
Western Blot.
Reactivities Human
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Recombinant protein
Specificity This antibody recognizes Human PRUNE.
Formulation PBS, pH 7.2
State: Purified
State: Liquid purified Ig fraction
Concentration 1 mg/ml
Purification Protein A Chromatography
Gene Name Homo sapiens prune exopolyphosphatase (PRUNE), transcript variant 1
Background PRUNE, the human homologue of the Drosophila gene, is located in 1q21.3, a region highly amplified in human sarcomas, malignant tumours of mesenchymal origin. Human prune (h-prune), a phosphoesterase DHH family appertaining protein, physically interacts with nm23-H1, a metastasis suppressor gene. h-prune is involved in cellular motility and metastasis formation. Metastatic breast cancers were found to overexpress h-prune; h-prune was also found to be highly expressed in colorectal and pancreatic cancers. Hence h-prune is considered useful as a marker for tumor aggressiveness.
Synonyms Protein prune homolog, hPrune, HTcD37, DRES17, DRES-17
Reference Data
Protein Pathways Purine metabolism

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.