NDRG4 (1-340) Mouse Monoclonal Antibody [Clone ID: 2G3]

CAT#: AM31976PU-N

NDRG4 (1-340) mouse monoclonal antibody, clone 2G3, Purified

Product Images

Western Blot analysis of NDRG4 expression in Raw 264.7 using Antibody.

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  Detection limit for recombinant GST tagged NDRG4 is approximately 3ng/ml as a capture antibody.

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  Human Brain, Cortex Neuropil: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Clone Name: 2G3
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 1/100.
  Western Blot: 1/500 - 1/1000.
• Reactivities: Human, Mouse
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: NDRG4 (AAH11795, 1 a.a. ~340 a.a) full length recombinant protein with GST tag
• Specificity: Recognizes NDRG4 at aa 1-340.
• Formulation: PBS, pH 7.2
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: 0.4 mg/ml
• Purification: Protein A Chromatography
• Gene Name: Homo sapiens NDRG family member 4 (NDRG4), transcript variant 2
• Database Link:
  Entrez Gene 234593 MouseEntrez Gene 65009 Human
• Background: The N-Myc downstream regulated gene (NDRG) family is comprised of four members, namely NDRG1, NDRG2, NDRG3 and NDRG4, all of which share 57-65% homology. NDRG4 (NDRG family member 4), also known as SMAP8 (smooth muscle-associated protein 8) or BDM1 (brain development-related molecule 1), is a 352 amino acid cytoplasmic protein that belongs to the NDRG family. Expressed specifically in brain and heart, NDRG4 is thought to function as a regulator of mitogenic signaling in vascular smooth muscle cells. Additionally, NDRG4 may play a role in early postnatal development and may mediate the differentiation and subsequent function of neuronal cells. NDRG4 is expressed as six isoforms (the first three of which are designated NDRG4- BVar, NDRG4-B and NDRG4-H) due to alternative splicing events
• Synonyms: BDM1, KIAA1180