MRP4 (ABCC4) Rat Monoclonal Antibody [Clone ID: M4I-80]
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Specifications
Product Data | |
Clone Name | M4I-80 |
Applications | IF, IHC, WB |
Recommended Dilution | Western blotting: Use at 1/20-1/50 dilution and anti-Rat-HRP. Immunocytochemistry: Use at 1/20-1/50 on Acetone Fixed Cytospin preparations. Immunohistochemisty on Frozen Sections: 1/20 on Acetone Fixed Frozen sections can be followed by incubation with Biotin conjugated Rabbit anti-Rat IgG (1/100) and and HRP-labeled Streptavidin (1/ 500). |
Reactivities | Human |
Host | Rat |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | A fusion protein containing the E. coli maltose binding protein and a fragment of the Human MRP4 protein corresponding to amino acids 372-431. |
Specificity | This Monoclonal antibody clone M4I-80 recognizes MRP4/ABCC4. The M4I-80 Mab also reacts with the Mouse orthologue of the transporter molecule (Mrp4). |
Formulation | State: Supernatant State: Serum Free Culture Supernatant Stabilizer: 0.7% BSA Preservative: 0.09% Sodium Azide |
Concentration | lot specific |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | ATP binding cassette subfamily C member 4 |
Database Link | |
Background | ABCC4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC proteins are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. |
Synonyms | Multidrug resistance-associated protein 4, MOAT-B |
Reference Data |
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