CD176 Mouse Monoclonal Antibody [Clone ID: A68-B/A11]

CAT#: AM32063PU-N

CD176 mouse monoclonal antibody, clone A68-B/A11, Purified

Specifications

Product Data

• Clone Name: A68-B/A11
• Applications: ELISA, FN, IHC
• Recommended Dilution: ELISA.
  Functional Appication: Blocking.
  Immunohistochemistry on Frozen Sections.
  Immunohistochemistry on Paraffin-Fixed Sections.
• Reactivities: Human
• Host: Mouse
• Isotype: IgM
• Clonality: Monoclonal
• Immunogen: Neuraminidase-treated Human red blood cells.
  The isolated splenocytes of the mice were electrofused with the myeloma cell line X63-Ag8.653.
• Specificity:

  This antibody clone A68-B/A11 recognize the carbohydrate epitope Thomsen-Friedenreich (asialo-glycophorin; GalNac-ßGal).
  It has no cross-reactivity with sialylated glycophorin.
  A68-B/A11 can be applied for the detection of cells with TF- antigens and is especially applicable for sensitive determination of neuraminidases.
  The mAb is capable to agglutinate desialylated red blood cells.

• Formulation: PBS
  State: Purified
  State: Liquid purified Ig fraction
  Preservative: 0.05% Sodium Azide
• Concentration: 0.1 mg/ml
• Background: The Thomsen Friedenreich antigen acts as an oncofoetal antigen, with low expression in normal adult tissues but increasing to foetal levels of expression in hyperplasia or malignancy. It is considered as a pan carcinoma marker. Can be applied for the detection of cells with TF antigen and is especially applicable for sensitive determination of neuraminidases.
• Synonyms: Thomsen-Friedenreich Antigen