Collagen III (COL3A1) Mouse Monoclonal Antibody [Clone ID: MC3-HA]
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Specifications
Product Data | |
Clone Name | MC3-HA |
Applications | ELISA, IHC, R, WB |
Recommended Dilution | ELISA. Western Blot. Radioimmunoassay. Immunohistochemistry on Frozen Sections: Fixation with acetone for 5 minutes at -20°C is recommended. Staining of paraffin material generally renders less successful results. Working Dilution: 1/20. |
Reactivities | Human |
Host | Mouse |
Isotype | IgM |
Clonality | Monoclonal |
Specificity | This Monoclonal antibody reacts exclusively with Human Collagen type III. It lacks cross reactivity with any other collagen type and plasma proteins. |
Formulation | State: Purified State: Lyophilized purified Ascites |
Reconstitution Method | Restore with 1 ml sterile water and add preservative if preferred. |
Concentration | lot specific |
Purification | PEG6000 precipitation + Sepharose 6B gel filtration |
Storage | Prior to reconstitution store at 2-8°C. |
Stability | Shelf life: one year from despatch. |
Database Link | |
Background | Collagen III is a fibrillar collagen that is found in extensible connective tissues such as skin, lung, and the vascular system, frequently in association with type I Collagen. Mutations in the gene are associated with Ehlers Danlos syndrome type IV, and with aortic and arterial aneurysms. Although alternate transcripts have been detected for this gene, they are the result of mutations; these mutations alter splicing, often leading to the exclusion of multiple exons. |
Synonyms | COL3A1 |
Reference Data |
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