CD62P (SELP) Mouse Monoclonal Antibody [Clone ID: CRC81]

CAT#: AM32328RP-N

CD62P (SELP) mouse monoclonal antibody, clone CRC81, PE

Specifications

Product Data

• Clone Name: CRC81
• Recommended Dilution: Flow Cytometry: 1 μg is the maximum amount of reagent required for 1 x 10e6 cells. For studies on platelets care should be taken to avoid activation of platelets during drawing of blood. Platelet activation markers are weakly expressed on platelets prepared from directly fixed normal blood. The expression is max. on thrombin (1 U/ml) stimulated, washed platelets. Fix cells or platelets with 1% paraformaldehyde, wash and adjust to approx. 10e8/ml for further incubations.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human platelets
• Specificity: The monoclonal antibody is directed against the CD62-antigen.
• Formulation: Label: PE
  State: Liquid purified Ig fraction
  Stabilizer: 0,9% BSA
  Absorption emission: 488 nm / 575 nm
• Conjugation: PE
• Storage:

  Store the antibody undiluted at 2-8°C.
  <b>DO NOT FREEZE!</b>
  This product is photosensitive and should be protected from light.

• Stability: Shelf life: one year from despatch.

• Gene Name: selectin P
• Database Link:
  Entrez Gene 6403 Human
• Background: CD62, an integral membrane sialoglycoprotein 140 kD, also designated GMP-140 (granule membrane protein 140) or PADGEM, which is expressed in platelet alpha granules that are translocated to the platelet surface upon activation with strong agonists. A similar protein, present in endothelial cell Weibel-Palade bodies, is transiently expressed on the surface of activated endothelial cells and functions as adhesion molecule for granulocytes. The antibody does not interfere with the functional activity of CD62 as an adhesion receptor for neutrophils.
• Synonyms: SELP, GMRP, GRMP, PADGEM, GMP-140, LECAM3