CD41 / ITGA2B Mouse Monoclonal Antibody [Clone ID: VM16a]

CAT#: AM32331PU-N

CD41 / ITGA2B mouse monoclonal antibody, clone VM16a, Purified

Specifications

Product Data

• Clone Name: VM16a
• Applications: FN, IF
• Recommended Dilution: Flow Cytometry.
  Functional Assay.
  Immunofluorescence.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Specificity:

  This antibody recognizes the intact platelet GPIIb/IIIa complex (alphaIIb/beta3), i.e. it does not bind to dissociated GPIIb or GPIIIa. The antibody reacts with human platelets and megakaryocytes. Apparent molecular weight under reducing conditions: GPIIIa; 110 kD; GPIIb alpha chain; 125 kD, beta chain; 25 kD. The antibody does not bind to platelets from patients with Glanzmann thrombasthenia and does not recognize the vitronectin receptor, which contains GPIIIa as a beta subunit (cf. CD61). VM16a inhibits platelet Fc-receptor dependent reactions due to the proposed topographical association of the platelet Fc-receptor and the glycoprotein IIb-IIIa complex.

• Formulation: PBS
  State: Purified
  State: Lyophilized purified Ig fraction
  Preservative: 0,09% sodium azide
• Reconstitution Method: Reconstitute with 1 ml sterile water.
• Purification: Ammonium sulfate + DEAE-cellulose, gradient elution
• Storage:

  Store the antibody undiluted at 2-8°C.

• Stability: Shelf life: one year from despatch.

• Synonyms: Integrin alpha-IIb, GP2B, ITGAB, GPalpha IIb