HLA Class II DR Mouse Monoclonal Antibody [Clone ID: LN-3]

CAT#: AM32359SU-N

HLA Class II DR mouse monoclonal antibody, clone LN-3, Supernatant


USD 445.00

2 Weeks*

Size
    • 1 ml

Product Images

Specifications

Product Data
Clone Name LN-3
Applications IHC
Recommended Dilution Immunohistochemistry on Paraffin Sections: 1/100. 
Positive Control: Human Spleen. 
LN-3 can be applied for the identification of HLA-DR positive germinal center derived B cell lymphomes, HLA-DR positive T cell lymphomas, HLA-positive leukemias and solid tumors in B5 fixed, paraffin embedded tissue.
Reactivities Human
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Human leukocyte antigen-DR
Specificity This antibody reacts with Human leukocyte antigen-DR (HLA-DR). The antibody clone LN-3 has lymph node germinal center and mantle zone B cell reactivity. 
It reacts with interdigitating histiocytes in T cell zones and with sinus histiocytes and endothelial cells. It has also tumor specificity and reactivity with normal nonlymphoid tissue. 
Cellular Localization: Cell membrane.
Formulation State: Supernatant
State: Liquid Serum Free Culture Supernatant
Stabilizer: 0.7% BSA
Preservative: 0.09% Sodium Azide
Storage

Store the antibody undiluted at 2-8°C.

Stability Shelf life: one year from despatch.

Background HLA DR, like other MHC class II molecules, is a transmembrane glycoprotein composed of an alpha chain (36 kDa) and a beta chain (27 kDa). It is expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, thymic epithelial cells and activated T lymphocytes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T helper cells. They therefore have a critical role in the initiation of the immune response.
Synonyms HLA-DR, HLA class II histocompatibility antigen DR, MHC class II antigen DR
Note Mol. Wt. of Antigeng: 36 kDa (alpha chain) and 27 kDa (beta chain).
Reference Data

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.