CD11c (ITGAX) Mouse Monoclonal Antibody [Clone ID: FK24]

CAT#: AM32414SU-N

CD11c (ITGAX) mouse monoclonal antibody, clone FK24, Ascites


USD 230.00

2 Weeks*

Size
    • 1 ml

Product Images

Specifications

Product Data
Clone Name FK24
Applications IF, IHC
Recommended Dilution

Immunocytochemistry.
Immunofluorescence.  
Recommended Dilutions:  1/5, Dilute antibody preferably in PBS plus 1% BSA and 0.01% Sodium Azide. 
Note: This antibody can be used for the identification of CD11c-positive cells using Immunofluorescence or immunoperoxidase procedures. It can thus be used for the identification of monocytes and granylocytes using either Immunofluorescence or immunoperoxidase procedures. In addition it seems useful for identification of myelomonocytic and monocytic leukemias.

Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Specificity

The antibody reacts with the alpha chain the 150 kD molecule of the CD11c/CD18 Integrin complex (g150/95) which is expressed on monocytes and in a lower density on granulocytes and NK-cells of peripheral blood. It also reacts with many myelomonocytic and monocytic leukemias and (weakly) with part of the T8 positive cells (OKM1-like). The Integrins are important molecules in cellular adhesion and cellular interactions.

Formulation State: Ascites
State: Liquid diluted Ascites
Storage

Store the antibody undiluted at 2-8°C.

Stability Shelf life: one year from despatch.

Background Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.
Synonyms ITGAX, Integrin alpha-X, Leu M5
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.