CD11c (ITGAX) Mouse Monoclonal Antibody [Clone ID: FK24]
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Product Data | |
Clone Name | FK24 |
Applications | IF, IHC |
Recommended Dilution | Immunocytochemistry. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Specificity | The antibody reacts with the alpha chain the 150 kD molecule of the CD11c/CD18 Integrin complex (g150/95) which is expressed on monocytes and in a lower density on granulocytes and NK-cells of peripheral blood. It also reacts with many myelomonocytic and monocytic leukemias and (weakly) with part of the T8 positive cells (OKM1-like). The Integrins are important molecules in cellular adhesion and cellular interactions. |
Formulation | State: Ascites State: Liquid diluted Ascites |
Storage | Store the antibody undiluted at 2-8°C. |
Stability | Shelf life: one year from despatch. |
Database Link | |
Background | Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. |
Synonyms | ITGAX, Integrin alpha-X, Leu M5 |
Reference Data |
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