Cd4 Rat Monoclonal Antibody [Clone ID: GK1.5]

CAT#: AM32703AF-N

Cd4 rat monoclonal antibody, clone GK1.5, Azide Free

Product Images

BALB/c Mouse splenocytes were stained with a 0.125 ug/106 cells anti-Mouse CD4 Antibody Cat.-No AM32703AF-N (Clone GK1.5) (purple) or Negative Control (green), followed by PE-conjugated Goat anti-Rat Ig (1/200 dilution).

Specifications

Product Data

• Clone Name: GK1.5
• Applications: FC, IF, IHC, IP
• Recommended Dilution: Flow Cytometry (Cell Surface): 0.125-1.0 μg/10⁶ cells.
  Immunofluorescence.
  Immunoprecipitation.
  Immunohistochemistry.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2b
• Clonality: Monoclonal
• Specificity: Recognizes Mouse CD4. Other species not tested.
• Formulation: PBS, pH 7.4
  State: Azide Free
  State: Liquid (sterile) purified IgG fraction
  Preservative: None
• Concentration: 0.5 mg/ml
• Purification: Protein G Chromatography
• Predicted Protein Size: 52 kDa
• Database Link:
  Entrez Gene 12504 Mouse
• Background: CD4 (cluster of differentiation 4) is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells. It is a member of the immunoglobulin superfamily. On T cells, it is the co-receptor for the T cell receptor (TCR) and amplifies the signal generated by the TCR by recruiting the tyrosine kinase lck that is essential for activating many molecules involved in the signaling cascade of an activated T cell. It is an important component of the immune system and is also the cellular receptor for HIV-1. It consists of a cytoplasmic tail, one transmembrane region, and four extracellular domains, D1-D4.
• Synonyms: T-cell surface antigen T4/Leu-3