Ficolin 2 (FCN2) Mouse Monoclonal Antibody [Clone ID: GN4]

CAT#: AM32977BT-N

Ficolin 2 (FCN2) mouse monoclonal antibody, clone GN4, Biotin, Purified

Specifications

Product Data

• Clone Name: GN4
• Applications: ELISA, IP
• Recommended Dilution: Immuno Assays.
  Immunoprecipitation.
  For Western blot of Non-Reduced samples we advise to use AM32978PU-N (Clone GN5).
  
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: L-Ficolin/P35 isolated from Human plasma
• Specificity: The monoclonal antibody GN4 recognizes L-Ficolin/P35.
• Formulation: PBS
  Label: Biotin
  State: Purified
  State: Liquid 0.2 µm filtered Ig fraction
  Stabilizer: 0.1% BSA
• Concentration: lot specific
• Conjugation: Biotin
• Storage: Store undiluted at 2-8°C.
  DO NOT FREEZE!
• Stability: Shelf life: one year from despatch.
• Database Link:
  Entrez Gene 2220 Human
• Background: Ficolins are a group of proteins containing both a collagen-like domain and a fibrinogen-like domain. They are found in various tissues. The domain organizations between ficolins and mannose binding lectin (MBL) are similar, although the carbohydrate-binding moieties are different. In man two types of ficolins (Lficolin/ P35 and H-ficolin) are present in serum and one type (M-ficolin) in cells. L-ficolin/P35 (also L-ficolin, ficolin L, EBP-37 or hucolin) is produced primarily by the liver. The association between L-ficolin/P35 and MASPs/sMAP is Ca²⁺-dependent. MASPs in L-ficolin/P35-MASP complexes have proteolytic activities for C4, C2 and C3. L-ficolin/P35 also shows opsonic activity.
• Synonyms: FCN2, FCNL, Ficolin2, Ficolin-B, Ficolin-beta, L-ficolin, Serum lectin p35, 37 kDa elastin-binding protein, EBP-37, Hucolin