MET Rat Monoclonal Antibody [Clone ID: BCI-3E7]

CAT#: AM32986PU-N

MET rat monoclonal antibody, clone BCI-3E7, Purified


USD 380.00

2 Weeks*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name BCI-3E7
Applications ELISA, FC, WB
Recommended Dilution Flow Cytometry: 1.2 µg/106 cells.
Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400.
Reactivities Human
Host Rat
Isotype IgG2b
Clonality Monoclonal
Immunogen cDNA encoding Human c-Met
Specificity Recognizes c-Met.
Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells.
Formulation PBS, pH 7.2
State: Purified
State: Liquid purified IgG fraction
Concentration lot specific
Purification Affinity Chromatography on Protein G
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Background c-MET is a receptor tyrosine kinase that is activated upon Hepatocyte Growth Factor (HGF) binding. c-MET is produced as a single-chain precursor and plays en essential role in embryonic development and wound healing. It belongs to the class of Singlepass type I membrane proteins and it is normally expressed by cells of epithelial origin while the expression of HGF is restricted to cells of mesenchymal origin in an almost perfect paracrine paradigm. Overexpression of c-MET can be found in several kinds of tumor progression.
Synonyms Hepatocyte growth factor receptor, MET, Scatter factor receptor, HGF/SF receptor, c-Met
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.