Gbgt1 (Forssman antigen) Rat Monoclonal Antibody [Clone ID: 117C9]

CAT#: AM33023PU-N

Gbgt1 (Forssman antigen) rat monoclonal antibody, clone 117C9, Purified


USD 390.00

2 Weeks*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name 117C9
Applications IHC
Recommended Dilution Immunohistochemistry on Frozen sections.
Reactivities Mouse
Host Rat
Isotype IgM
Clonality Monoclonal
Immunogen The antibody 117C9 is a rat anti-Forrsman glycosphingolipid (FGL) antibody derived by fusing mouse myeloma cells with spleen cells from a Rat immunized with Mouse mammary tumors.
Specificity Clone 33B12 and 117C9 detect overlapping epitopes on the Forssman glycolipid hapten (GalNA1- c3aG alNAcD1 -3GalaI-4GalB1-4GlcBl-lCer).
Clone 117C9 recognizes the internal sugar sequence GalNAqYlBGal. The 117C9 antibody does not react exclusively with the Forssman antigen. In a lipid extract fractionated by Folch partition of Mouse mammary tumors the antibody also detects other glycolipid.
Formulation PBS
State: Purified
State: Liquid purified Ig fraction
Preservative: 0.09% Sodium Azide
Concentration 1.0 mg/ml
Background The Forssman glycolipid is a glycosylceramide possessing a neutral pentasaccharide head group, referred to as the Forssman antigen (Fa) and is a member of the globoseries glycolipid family.
Fa has been identified in a number of mammals and exhibits heterogeneity with respect to developmental and cell-type expression among species. Some studies have reported the presence of the Fa in certain human embryonic and tumor cells.
The majority of human individuals have undetectable levels of Fa.
Gastric and colonic tumors from Fa-negative patients, however, contained relatively high levels of Fa. Moreover, compared with normal lung tissue, many lung cancers contained elevated levels of Fa.
These observations arouse interest in Fa for a possible role as a human tumor antigen.
Synonyms A3GALNT; FS; MGC44848; UDP-GalNAc; UNQ2513
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.