CD98 (SLC3A2) Mouse Monoclonal Antibody [Clone ID: UM7F8]

CAT#: AM33318PU-T

CD98 (SLC3A2) mouse monoclonal antibody, clone UM7F8, Purified

Specifications

Product Data

• Clone Name: UM7F8
• Applications: FC, IF, IHC, IP, WB
• Recommended Dilution:
  Comitogenic with soluble anti-CD2 and immobilized anti-CD3 monoclonal Antibodies.
  Western Blot: 0.5-1 µg/ml.
  Flow Cytometry: 0.5-1 µg/10⁶ cells.
  Immunofluorescence: 0.5-1 µg/ml.
  Immunoprecipitation: 1-2 µg/500 µg protein.
  Immunohistochemistry on Frozen Sections: 0.5-1 µg/ml for 30 minutes at RT.
  Positive Control: HL-60, Jurkat, MG63, HUT-78, K562, YT, U937, Hep-G2 cells, Tonsil.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Molt 13 T cell line
• Specificity: Cellular Localization: Apical cell membrane, Cell junction, Cell membrane, Lysosome membrane, Melanosome
• Formulation: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Concentration: lot specific
• Purification: Protein A/G Chromatography
• Conjugation: Unconjugated
• Storage: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: Heterodimer (125kDa) made of a disulfide-linked glycosylated heavy chain of approximately 80-90kDa and a non-glycosylated light chain
• Gene Name: solute carrier family 3 member 2
• Database Link:
  Entrez Gene 6520 Human
  UniProt ID P08195
• Background: CD98 exits as a heterodimer containing a disulphide-linked glycosylated heavy chain and a non-glycosylated light chain. It is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through disulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized.
• Synonyms: 4F2, 4F2HC, 4T2HC, CD98C; MDU1; NACAE; Slc3a2; Solute Carrier Family 3 (activators of dibasic and neutral amino acid transport) Member 2, E16, LAT1, MPE16, hLAT1